What is DNA fragmentation & can it be caused by free radicals?
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Filed under: Alternative Medicine
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Yes. Free radicals (and this is usually going to be OH free radicals) chemically attack the phosphodiester bonds that hold the nucleotides of DNA together. This causes breaks in the DNA (fragmentation).
If you have cancer and get radiation therapy, this is how they kill the cancer cells. They bombard you with radiation, which splits water molecules and releases the OH free radical. These in turn attack the DNA and kill the (cancer) cell.